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Professor Sir Fraser Stoddart, the Board of Trustees Professor of Chemistry at the Northwestern University, United States of America, visited Hong Kong in November 2019. The Innovation and Technology Bureau took the opportunity to invite Professor Stoddart to share his inspirational story on scientific and innovation pursuit through an interview. Professor Sir Fraser Stoddart, along with Jean-Pierre Sauvage and Ben Feringa, won the 2016 Nobel Prize in Chemistry for the design and synthesis of artificial molecular machines. Dr Ken Cham Fai Leung, Associate Professor of the Department of Chemistry of Hong Kong Baptist University, was the Croucher research fellow in the research group of Professor Stoddart during his time at University of California, Los Angeles. He assisted in conducting the interview with Professor Stoddart. In the dialogue with Dr Leung, Professor Stoddart shared his journey to a stereochemistry giant (video). Based on his personal experience, Professor Stoddart shared the lessons on success (video) and encouraged students and research fellows to enjoy exploring the unknown (video) to make life journey satisfying. Here is an abridged version of his sharing “Advice for Students” (video) – Permission is required in adopting, reproducing or redistributing the videos. Please send your request to email@example.com.